| # | Coureur | Nat | MSR | RVV | PR | LBL | GdL | Team | Periode |
|---|---|---|---|---|---|---|---|---|---|
| 19 | Eddy Merckx | BEL | 7 | 2 | 3 | 5 | 2 | 1966-1976 | |
| 11 | Roger De Vlaeminck | BEL | 3 | 1 | 4 | 1 | 2 | 1970-1979 | |
| 9 | Sean Kelly | IRL | 2 | 0 | 2 | 2 | 3 | 1983-1992 | |
| 9 | Fausto Coppi | ITA | 3 | 0 | 1 | 0 | 5 | 1946-1954 | |
| 9 | Costante Girardengo | ITA | 6 | 0 | 0 | 0 | 3 | 1918-1928 | |
| 8 | Rik Van Looy | BEL | 1 | 2 | 3 | 1 | 1 | 1958-1965 | |
| 7 | Fabian Cancellara | ZWI | 1 | 3 | 3 | 0 | 0 | 2006-2014 | |
| 7 | Tom Boonen | BEL | 0 | 3 | 4 | 0 | 0 | 2005-2012 | |
| 7 | Gino Bartali | ITA | 4 | 0 | 0 | 0 | 3 | 1936-1950 | |
| 6 | Johan Museeuw | BEL | 0 | 3 | 3 | 0 | 0 | 1993-2002 | |
| 6 | Moreno Argentin | ITA | 0 | 1 | 0 | 4 | 1 | 1985-1991 | |
| 6 | Francesco Moser | ITA | 1 | 0 | 3 | 0 | 2 | 1975-1984 | |
| 6 | Alfred De Bruyne | BEL | 1 | 1 | 1 | 3 | 0 | 1956-1959 | |
| 6 | Alfredo Binda | ITA | 2 | 0 | 0 | 0 | 4 | 1925-1931 | |
| 6 | Henri Pélissier | FRA | 1 | 0 | 2 | 0 | 3 | 1911-1921 | |
| 5 | Philippe Gilbert | BEL | 0 | 1 | 1 | 1 | 2 | 2009-2019 | |
| 5 | Paolo Bettini | ITA | 1 | 0 | 0 | 2 | 2 | 2000-2006 | |
| 5 | Michele Bartoli | ITA | 0 | 1 | 0 | 2 | 2 | 1996-2003 | |
| 5 | Bernard Hinault | FRA | 0 | 0 | 1 | 2 | 2 | 1977-1984 | |
| 5 | Rik Van Steenbergen | BEL | 1 | 2 | 2 | 0 | 0 | 1944-1954 | |
| 5 | Gaetano Belloni | ITA | 2 | 0 | 0 | 0 | 3 | 1915-1928 | |
| 4 | Mathieu van der Poel | NED | 1 | 2 | 1 | 0 | 0 | ADC | 2020-2023 |
| 4 | Tadej Pogacar | SLO | 0 | 1 | 0 | 1 | 2 | UAD | 2021-2023 |
| 4 | Alejandro Valverde Belmonte | SPA | 0 | 0 | 0 | 4 | 0 | 2006-2017 | |
| 4 | Erik Zabel | DUI | 4 | 0 | 0 | 0 | 0 | 1997-2001 | |
| 4 | Hennie Kuiper | NED | 1 | 1 | 1 | 0 | 1 | 1981-1985 | |
| 4 | Jan Raas | NED | 1 | 2 | 1 | 0 | 0 | 1977-1983 | |
| 4 | Walter Godefroot | BEL | 0 | 2 | 1 | 1 | 0 | 1967-1978 | |
| 4 | Felice Gimondi | ITA | 1 | 0 | 1 | 0 | 2 | 1966-1974 | |
| 4 | Germain Derijcke | BEL | 1 | 1 | 1 | 1 | 0 | 1953-1958 | |
| 4 | Louison Bobet | FRA | 1 | 1 | 1 | 0 | 1 | 1951-1956 | |
| 4 | Gaston Rebry | BEL | 0 | 1 | 3 | 0 | 0 | 1931-1935 | |
| 4 | Alfons Schepers | BEL | 0 | 1 | 0 | 3 | 0 | 1929-1935 | |
| 3 | Vincenzo Nibali | ITA | 1 | 0 | 0 | 0 | 2 | 2015-2018 | |
| 3 | Oscar Freire Gomez | SPA | 3 | 0 | 0 | 0 | 0 | 2004-2010 | |
| 3 | Damiano Cunego | ITA | 0 | 0 | 0 | 0 | 3 | 2004-2008 | |
| 3 | Peter Van Petegem | BEL | 0 | 2 | 1 | 0 | 0 | 1999-2003 | |
| 3 | Andrea Tafi | ITA | 0 | 1 | 1 | 0 | 1 | 1996-2002 | |
| 3 | Andrei Tchmil | MDA | 1 | 1 | 1 | 0 | 0 | 1994-2000 | |
| 3 | Eric Leman | BEL | 0 | 3 | 0 | 0 | 0 | 1970-1973 | |
| 3 | Jo de Roo | NED | 0 | 1 | 0 | 0 | 2 | 1962-1965 | |
| 3 | Tom Simpson | GBR | 1 | 1 | 0 | 0 | 1 | 1961-1965 | |
| 3 | Emile Daems | BEL | 1 | 0 | 1 | 0 | 1 | 1960-1963 | |
| 3 | Fiorenzo Magni | ITA | 0 | 3 | 0 | 0 | 0 | 1949-1951 | |
| 3 | Achiel Buysse | BEL | 0 | 3 | 0 | 0 | 0 | 1940-1943 | |
| 3 | Romain Gijssels | BEL | 0 | 2 | 1 | 0 | 0 | 1931-1932 | |
| 3 | René Vermandel | BEL | 0 | 1 | 0 | 2 | 0 | 1921-1924 | |
| 3 | Giovanni Brunero | ITA | 1 | 0 | 0 | 0 | 2 | 1922-1924 | |
| 3 | Octave Lapize | FRA | 0 | 0 | 3 | 0 | 0 | 1909-1911 | |
| 3 | Léon Houa | BEL | 0 | 0 | 0 | 3 | 0 | 1892-1894 | |
| 2 | Remco Evenepoel | BEL | 0 | 0 | 0 | 2 | 0 | SOQ | 2022-2023 |
| 2 | Jakob Fuglsang | DEN | 0 | 0 | 0 | 1 | 1 | IPT | 2019-2020 |
| 2 | Peter Sagan | SVK | 0 | 1 | 1 | 0 | 0 | TEN | 2016-2018 |
| 2 | John Degenkolb | DUI | 1 | 0 | 1 | 0 | 0 | DSM | 2015-2015 |
| 2 | Alexander Kristoff | NOR | 1 | 1 | 0 | 0 | 0 | UXT | 2014-2015 |
| 1 | Matej Mohoric | SLO | 1 | 0 | 0 | 0 | 0 | TBV | 2022-2022 |
| 1 | Dylan van Baarle | NED | 0 | 0 | 1 | 0 | 0 | TJV | 2022-2022 |
| 1 | Kasper Asgreen | DEN | 0 | 1 | 0 | 0 | 0 | SOQ | 2021-2021 |
MSR: Milano - Sanremo, RVV: Ronde van Vlaanderen, PR: Paris - Roubaix, LBL: Liège - Bastogne - Liège, GdL: Giro di Lombardia/Il Lombardia